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Molecular Basis of Inheritance
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» L-6 : Molecular Basis of Inheritance
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Molecular Basis of Inheritance
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Bihar Board
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Class 12th
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English Medium
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Science
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Biology
» L-6 : Molecular Basis of Inheritance
Objective Questions (MCQs)
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Multiple Choice
Verified
ID- 2690
BSEB, 2020 (A)
1. Which one of the following in mobile genetic elements?
(A) Split gene
(B) Transposon
(C) Jumping gene
(D) Both (B) and (C)
Multiple Choice
Verified
ID- 2691
BSEB, 2019 (C)
2. Lac operon consists of how many structural ganes?
(A) 1 (a)
(B) 2 (y and z)
(C) 3 (z, y and a)
(D) four
Multiple Choice
Verified
ID- 2692
BSEB, 2019 (C)
3. Which among the following anticodon is meant for "GAC" condon of DNA?
(A) CTG
(B) CUG
(C) Both A & B
(D) CAG
Multiple Choice
Verified
ID- 2693
BSEB, 2019 (C)
4. Name the genetic material in TMV (Tabacco Mosaic virus).
(A) DNA
(B) RNA single standed
(C) RNA double standed
(D) R-DNA
Multiple Choice
Verified
ID- 2694
BSEB, 2019 (C)
5. Which type of nitrogenous bases of Purine occur in DNA and RNA?
(A) Adenine
(B) Guranine
(C) Both (A) and (B)
(D) Cytosine
Multiple Choice
Verified
ID- 2695
BSEB, 2020 (A)
6. Which one is initiation codon?
(A) UAG and UGA
(B) AUG and GUG
(C) UAA and UAG
(D) UAA and UGA
Multiple Choice
Verified
ID- 2696
BSEB, 2020 (A)
7. What will be the base sequence of DNA against the base sequence 'AUCGCCUGA' of RNA?
(A) TTGCGGACT
(B) TAGCGGACT
(C) UAGCGGACU
(D) TAGCCCACT
Multiple Choice
Verified
ID- 2697
BSEB, 2020 (A)
8. The function of polymerase chain reaction is:
(A) Transcription
(B) Translation
(C) Both (A) and (B)
(D) DNA amplification
Multiple Choice
Verified
ID- 2698
BSEB, 2013; 2016
9. The phenotypic ratio in a dihybrid cross is:
(A) 3 : 1
(B) 1 : 2 : 1
(C) 9 : 7
(D) 9 : 3 : 3 : 1
Multiple Choice
Verified
ID- 2699
BSEB, 2013
10. Gene for hypertrichosis (having pinna) is present on:
(A) X-chromosome
(B) Y- chromosome
(C) Sex chromosome
(D) Autosome
Multiple Choice
Verified
ID- 2700
BSEB, 2009, 2021 (A)
11. A gene pair hides the effect of another gene pair. The phenomenon is:
(A) Epistasis
(B) Dominance
(C) Mutation
(D) None of these
Multiple Choice
Verified
ID- 2701
BSEB, 2009, 2021 (A)
12. In a DNA molecule, the cytosine is 18%. The percentage of adenine is:
(A) 64
(B) 36
(C) 82
(D) 32
Multiple Choice
Verified
ID- 2702
BSEB, 2009
13. Which part of the donor's eye is used for grafting in order to cure certain cases of blindness?
(A) Lens
(B) Retina
(C) Cornea
(D) Choroid
Multiple Choice
Verified
ID- 2703
BSEB, 2009
14. RNA differs from NDA in containing:
(A) phosphate
(B) ribose
(C) deoxyribose
(D) cytosine
Multiple Choice
Verified
ID- 2726
BSEB, 2009, 2021 (A)
15. A sequence of three bases on
t
RNA which binds to
m
RNA codon is:
(A) triplet
(B) non-sense
(C) anticodon
(D) termination codon
Multiple Choice
Verified
ID- 2727
BSEB, 2009
16. The number of linkage groups in a cell having 2
n
= 14 is:
(A) 5
(B) 10
(C) 7
(D) 14
Multiple Choice
Verified
ID- 2728
BSEB, 2012, 2021 (A)
17. In which stage does crossing over take place:
(A) Leoptotene
(B) Cytokinesis
(C) Pachytene
(D) Diakinesis
Multiple Choice
Verified
ID- 2729
BSEB, 2012
18. Nucleic acids are polymers of:
(A) Nucleotides
(B) Nucleosides
(C) Amino acids
(D) Nucleoproteins
Multiple Choice
Verified
ID- 2730
BSEB, 2011
19. Pyrimidines present in DNA are:
(A) Thymine and Cytosine
(B) Adenine and Guanine
(C) Cytosine and Uracil
(D) Thyminie and Uracil
Multiple Choice
Verified
ID- 2731
BSEB, 2011, 2012 (A)
20. Crossing over takes place in:
(A) Zygotene
(B) Leptotene
(C) Pachytene
(D) Metaphase
Multiple Choice
Verified
ID- 2733
BSEB, 2010
21. Which disease is due to haemoglobin's defect?
(A) Down's syndrome
(B) Phenyl ketonuria
(C) Klinefelter syndrome
(D) Sickle cell anaemia
Multiple Choice
Verified
ID- 2734
BSEB, 2010, 2021 (A)
22. Pyrimidines is present in RNA are:
(A) Cytosine and Thymine
(B) Adenine and Guanine
(C) Cytosine and Uracil
(D) Thymine and Uracil
Multiple Choice
Verified
ID- 2735
BSEB, 2010
23. PCR method is useful for:
(A) DNA synthesis
(B) Protein synthesis
(C) Amino acids synthesis
(D) DNA amplification
Multiple Choice
Verified
ID- 2737
BSEB, 2015
24. How many codons are present in inheritance codan:
(A) 4
(B) 16
(C) 32
(D) 64
Multiple Choice
Verified
ID- 2739
BSEB, 2015, 2021 (A)
25. Operon model was proposed by:
(A) Waston and crick
(B) Nirenberg
(C) Jacob and Monad
(D) none of these
Multiple Choice
Verified
ID- 2740
26. DNA and RNA differ by:
(A) Nitrogen bases and sugars
(B) Nitrogen bases and phosphate groups
(C) Number of C-atoms in sugars
(D) Sugar and phosphate groups
Multiple Choice
Verified
ID- 2742
27. Triplet UUU codes for:
(A) Leucine
(B) Methionine
(C) Phenylalanine
(D) Glycine
Multiple Choice
Verified
ID- 2744
28. Who discovered DNA polymerase:
(A) Okazaki
(B) Waston and Crick
(C) Meselson and Stahl
(D) Kornberg
Multiple Choice
Verified
ID- 2745
29. Khorana was awarded nobel prize for:
(A) Discovering DNA
(B) Discovering RNA
(C) Chemical synthesis of gene
(D) Discovering DNA polymerase
Multiple Choice
Verified
ID- 2747
30. A gene of an operon which forms the repressor protein is:
(A) Operator
(B) Promoter
(C) Regulator
(D) Structual
Multiple Choice
Verified
ID- 2748
BSEB, 2011, 2013, 2021 (A)
31. Anticodon found in:
(A) on DNA
(B) on tRNA
(C) on rRNA
(D) on mRNA
Multiple Choice
Verified
ID- 2753
32. In Sickle Cell Anaemia, the change in the shape of RBC from biconcave disc to sickle cell like structure is due to:
(A) Mutant Hb molecule undergo polymerization under low O
2
tension.
(B) Single base substitutions of the 6
th
codon of β-globin gene from GAG to GUG
(C) Substitution of Glutamic Acid by valine at 6
th
position of β-globin chain of Hb
(D) All of these
Multiple Choice
Verified
ID- 2754
BSEB, 2018 (C)
33. The coding sequence of monocistronic structural gene is called:
(A) Intron
(B) Exon
(C) Cistron
(D) Recon
Multiple Choice
Verified
ID- 2755
BSEB, 2018 (C)
34. Which of the following is a average no. of adenylate residues at 3' end in a template stands during tailing of transcriptional process of Eukaryotic RNA?
(A) 600 – 800
(B) 100 – 200
(C) 200 – 300
(D) 50 – 100
Multiple Choice
Verified
ID- 2762
35. DNA fragments are joined in a correct sequence by:
(A) DNA ligase
(B) RNA polymerase
(C) Helicase
(D) DNA polymerase
Multiple Choice
Verified
ID- 2763
BSEB, 2018 (C)
36. The Govt organzation which make the decision regarding validity of GM research and the safety of introducting GM organism for public service is:
(A) Genetically Engineered Approval Committee
(B) Genetically Engineered Management Committee
(C) Genetically Engineered Monitoring Authority
(D) None of these
Multiple Choice
Verified
ID- 2764
BSEB, 2018 (C)
37. Satellite DNA is useful tool in:
(A) Sex determination
(B) Forensic science
(C) Genetic engineering
(D) Organ Transplantation
Multiple Choice
Verified
ID- 2765
BSEB, 2018 (C)
38. The size of the variable number of tendem repeats (VNTR) varies from:
(A) 0.1 to 20 (kb)
(B) 20 to 150 (kb)
(C) 100 to 1000 (kb)
(D) 0.001 to 0.1 (kb)
Multiple Choice
Verified
ID- 2766
BSEB, 2019 (A)
39. Amplification of gene for interest may be done by:
(A) MMR
(B) PCR
(C) MRI
(D) All of these
Multiple Choice
Verified
ID- 2767
BSEB, 2019 (A)
40. RNAi is used to control pests on which plant?
(A) Tobacco
(B) Mango
(C) Potato
(D) Poppy
Multiple Choice
Verified
ID- 2768
BSEB, 2019 (A)
41. For induction of alien DNA in host cell we may use:
(A) Gene gun
(B) Micro-pipette
(C) Both (A) & (B)
(D) None of these
Multiple Choice
Verified
ID- 2769
42. One turn of the helix in β-from DNA is approximately.
(A) 20 Å
(B) 2 nm
(C) 20 nm
(D) 3.4 nm
Multiple Choice
Verified
ID- 2770
BSEB, 2020 (A)
43. Okazaki fragment is:
(A) RNA (RNA primers)
(B) Small segments of DNA on leading stand
(C) Small segments of DNA on lagging stand
(D) None of these
Multiple Choice
Verified
ID- 2771
44. One of these is not prepared directly from DNA:
(A) m-RNA
(B) t-RNA
(C) r-RNA
(D) Protein
Multiple Choice
Verified
ID- 2772
45. Coiling of DNA duplex is:
(A) Left handed
(B) Right handed
(C) Parallel
(D) All of these
Multiple Choice
Verified
ID- 2773
46. DNA double helix model was given by:
(A) Knoll and Ruska
(B) Khorana
(C) Watson and Crick
(D) Priestley
Multiple Choice
Verified
ID- 2774
BSEB, 2019 (A)
47. Synthesis of RNA on DNA template is known as:
(A) Translation
(B) Transcription
(C) Transduction
(D) Replication
Multiple Choice
Verified
ID- 2775
BSEB, 2019 (A)
48. Uracil is related to:
(A) RNA
(B) DNA
(C) Both (A) and (B)
(D) None of these
Multiple Choice
Verified
ID- 2776
49. RNA is genetic material in:
(A) prokaryotes
(B) eukaryotes
(C) Tobacco Mosaic Virus (TMV)
(D) E. coil
Multiple Choice
Verified
ID- 2777
50. The year 2003 was celebrated on the 15th anniversary of discovered by:
(A) Transposons by Barbara MC clintock
(B) Structure of DNA by Waston and Crick
(C) Mendel's laws of inheritance
(D) biotechnology by Kary Mullis
Multiple Choice
Verified
ID- 2835
51. Which of the following phenomena was experimentally proved by Meselson and Stahl?
(A) Transformation
(B) Transduction
(C) Semi-conservative DNA replication
(D) Central dogma
Multiple Choice
Verified
ID- 2836
BSEB, 2011, 2021 (A)
52. Nucleoside is:
(A) Sugar + a nitrogenous base
(B) Sugar + Phosphate
(C) Nitrogenous base + Phosphate
(D) None of these
Multiple Choice
Verified
ID- 2837
BSEB, 2021 (A)
53. Purine bases of DNA are:
(A) Adenine and Cytosine
(B) Cytosine and Thymine
(C) Adenine and Guanine
(D) None of these
Multiple Choice
Verified
ID- 2838
54. Methyl guanosine triphosphate is added to the 5' end of hrRNA in a progress of:
(A) splicing
(B) capping
(C) tailing
(D) none of these
Multiple Choice
Verified
ID- 2839
55. Polycistronic messenger RNA (mRNA) usually occurs in:
(A) bacteria
(B) prokaryotes
(C) eukaryotes
(D) both 'A' and 'B'
Multiple Choice
Verified
ID- 2840
56. Transcription unit:
(A) starts with TATA box
(B) starts with pallendrous regions and ends with rho factor
(C) starts with promotor region and end in terminator region
(D) starts with CAAT region
Multiple Choice
Verified
ID- 2841
57. The three codons with result in the termination of polypeptide chain in synthesis are:
(A) UAA, UAG, GUA
(B) UAA, UAG, UGA
(C) UAA, UGA, UUA
(D) UGU, UAG, UGA
Multiple Choice
Verified
ID- 2842
58. Some amino acid are coded by more than one codan, hence the genetic code is:
(A) overlapping
(B) degenerate
(C) wobbled
(D) unambiguous
Multiple Choice
Verified
ID- 2843
59. Amino acids which are specified by single codons are:
(A) phenylalanine and arginine
(B) tryptophan and methionine
(C) valine and proline
(D) methionine and arginine
Multiple Choice
Verified
ID- 2844
60. UTRs are the untranslated regions present on:
(A) rRNA
(B) tRNA
(C) mRNA
(D) hnRNA
Multiple Choice
Verified
ID- 2845
61. During expression of an operon, RNA Polymerase binds to:
(A) structural gene
(B) regulator gene
(C) operator
(D) promoter
Multiple Choice
Verified
ID- 2846
62. Regulations of gene expression occurs at the level of:
(A) transcription
(B) processing/splicing
(C) translation
(D) all of these
Multiple Choice
Verified
ID- 2847
63. Human genome consists of approximately:
(A) 3 x 10
9
(B) 6 x 10
9
bp
(C) 20,000 – 25,000 bp
(D) 2.2 x 10
4
bp
Multiple Choice
Verified
ID- 2848
64. Estimated number of gene in human beings is:
(A) 3,000
(B) 80,000
(C) 20,500
(D) 3 x 10
9
Multiple Choice
Verified
ID- 2849
65. In a DNA strand the nucleotides are linked together by:
(A) glycosidic bonds
(B) phosphodiester bonds
(C) poptide bonds
(D) hydrogen bonds
Multiple Choice
Verified
ID- 2850
66. A nucleoside differs from a nucleotide. It lacks the:
(A) base
(B) sugar
(C) phosphate group
(D) hydroxyl group
Multiple Choice
Verified
ID- 2851
67. Both deoxyribose and ribose belong to class of sugars called:
(A) trioses
(B) hexoses
(C) pentoses
(D) polysacccharides
Multiple Choice
Verified
ID- 2852
68. The first genetic materials could be:
(A) protein
(B) carbohydrates
(C) DNA
(D) RNA
Multiple Choice
Verified
ID- 2853
69. The human chromosome which the highest and least number of gene in them are respectively:
(A) Chromosome 21 and Y
(B) Chromosome 1 and X
(C) Chromosome 1 and Y
(D) Chromosome X and Y
Multiple Choice
Verified
ID- 2854
70. Who amongst the following scientists had no contribution in the development of the double helix model of the structure of DNA?
(A) Rosalind Franklin
(B) Maurice Wilkins
(C) Erwin Charagaff
(D) Meselson and Stahl
Multiple Choice
Verified
ID- 2855
71. Which of the following steps in transcription is catalysed by RNA polymerase?
(A) Initiation
(B) Elongation
(C) Termination
(D) All of the above
Multiple Choice
Verified
ID- 2856
72. Control of gene expression takes place at the travel of:
(A) transcription
(B) translation
(C) Both 'A' and 'B'
(D) none of the above
Multiple Choice
Verified
ID- 2857
73. In some viruses, DNA is synthesised by using RNA as template. Such a DNA is called:
(A) A-DNA
(B) B-DNA
(C) c DNA
(D) r DNA
Multiple Choice
Verified
ID- 2858
74. The RNA Polymerase holoenzyme transcribes:
(A) the promoter, structural gene and the terminator region
(B) The promoter and terminator region
(C) The structural gene and the terminator region
(D) The structural gene only
Multiple Choice
Verified
ID- 2859
75. In E. coil, the lac operon gets switched on when:
(A) lactose is present and it binds to the repressor
(B) repressor binds to operator
(C) RNA polymerase binds to the operator
(D) lactose is present and it binds to RNA polymerase
Multiple Choice
Verified
ID- 2860
BSEB, 2016
76. Trisomy (2
n
1) causes retardation in child, which is known as:
(A) Philadelphia
(B) Down's Syndrome
(C) Albinism
(D) None of these
Multiple Choice
Verified
ID- 2861
BSEB, 2016
77. DNA fingerprinting is:
(A) DNA typing
(B) DNA profiling
(C) Both 'A' and 'B'
(D) base paring
Multiple Choice
Verified
ID- 2862
BSEB, 2016 (C), 2017 (A), 2017 (C), 2021 (A)
78. DNA is genetic material of:
(A) T.M.V.
(B) Bacteriophage
(C) 'A' and 'B' both
(D) None of these
Multiple Choice
Verified
ID- 2863
79. Which of the nitrogenous base is not present in RNA:
(A) Thymine
(B) Cytosine
(C) Guarnine
(D) Adenine
Multiple Choice
Verified
ID- 2864
BSEB, 2017 (A), 2021 (A)
80. Operon Model is representation of:
(A) Gene synthesis
(B) Gene expression
(C) Gene regulation
(D) Gene function
Multiple Choice
Verified
ID- 2865
BSEB, 2017 (A), 2017 (C)
81. Which nitrogenous base is present in DNA?
(A) Thymine
(B) Uracil
(C) Guanine
(D) Cytosine
Multiple Choice
Verified
ID- 2866
BSEB, 2017 (A), 2017 (C)
82. Formation of m RNA from DNA is called:
(A) Transcription
(B) Replication
(C) Translation
(D) None
Multiple Choice
Verified
ID- 2867
BSEB, 2018 (A)
83. Which of the following is involved in transcription of t RNA, 5Sr RNA and Sn RNA of eukaryotes?
(A) RNA Polymerase I
(B) RNA Polymerase II
(C) RNA Polymerase III
(D) All of these